Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hillen, M. E.
Right arrow Articles by Sage, J. I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hillen, M. E.
Right arrow Articles by Sage, J. I.
NEUROLOGY 1996;47:1180-1183
© 1996 American Academy of Neurology

Nonmotor fluctuations in patients with Parkinson's disease

Machteld E. Hillen, MD and Jacob I. Sage, MD

From the Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ.
Received February 1, 1996. Accepted in final form March 25, 1996.
Address correspondence and reprint requests to Dr. Jacob I. Sage, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, CN 19, New Brunswick, NJ 08903.

We studied the nature and frequency of nonmotor "off" phenomena in 130 consecutive patients with Parkinson's disease (PD) with motor fluctuations.Twenty-two patients (17%) experienced nonmotor fluctuations as an end-of-dose phenomenon. Previously unreported, or little appreciated, nonmotor "off" states include sensory dyspnea, nausea, facial flushing, cough, hunger, unilateral limb edema, proximal limb pain, and trigeminal neuralgia-like pain. We attempted treatment modification in 12 of 22 patients; nonmotor "off" symptoms improved in nine of these 12 patients (75%). Recognizing these phenomena will prevent unnecessary tests and treatments.

NEUROLOGY 1996;47: 1180-1183




This article has been cited by other articles:


Home page
 Therapeutic Advances in Neurological DisordersHome page
S. H. Isaacson and R. A. Hauser
Review: Improving symptom control in early Parkinson's disease
Therapeutic Advances in Neurological Disorders, November 1, 2009; 2(6): 393 - 400.
[Abstract] [PDF]

Home page
 Cleveland Clinic Journal of MedicineHome page
M. PANDYA, C. S. KUBU, and M. L. GIROUX
Parkinson disease: Not just a movement disorder
Cleveland Clinic Journal of Medicine, December 1, 2008; 75(12): 856 - 864.
[Abstract] [Full Text] [PDF]

Home page
 The Annals of PharmacotherapyHome page
W. Simonson, R. A Hauser, and A. H. Schapira
Role of the Pharmacist in the Effective Management of Wearing-Off in Parkinson's Disease
Ann. Pharmacother., November 1, 2007; 41(11): 1842 - 1849.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
A H V Schapira
Present and future drug treatment for Parkinson's disease
J. Neurol. Neurosurg. Psychiatry, November 1, 2005; 76(11): 1472 - 1478.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
A. Sailer, G. F. Molnar, G. Paradiso, C. A. Gunraj, A. E. Lang, and R. Chen
Short and long latency afferent inhibition in Parkinson's disease
Brain, August 1, 2003; 126(8): 1883 - 1894.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
T. Witjas, E. Kaphan, J. P. Azulay, O. Blin, M. Ceccaldi, J. Pouget, M. Poncet, and A. A. Cherif
Nonmotor fluctuations in Parkinson's disease: Frequent and disabling
Neurology, August 13, 2002; 59(3): 408 - 413.
[Abstract] [Full Text] [PDF]

Home page
 Postgrad. Med. J.Home page
K Walsh and G Bennett
Parkinson's disease and anxiety
Postgrad. Med. J., February 1, 2001; 77(904): 89 - 93.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1996 by AAN Enterprises, Inc.