Neurology
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NEUROLOGY 1996;47:1374-1378
© 1996 American Academy of Neurology

Hypomanic symptoms caused by herpes simplex encephalitis

C. M. Fisher, MD

From the Neurology Service, Massachusetts General Hospital, Boston, MA.
Supported by the Joseph Yanofsky Fund.
Received November 29, 1995. Accepted in final form April 1, 1996.
Address correspondence and reprint requests to Dr. C. M. Fisher, Neurology Service, Massachusetts General Hospital, Fruit Street, Boston, MA 02114.

This is a case report of a brief episode of rather typical hypomanic symptoms in the acute phase of presumed herpes simplex encephalitis in a young woman.I infer that the hypomanic episode was triggered from the anterior inferomedial temporal lobe or limbic system, the presumed cerebral substrate of the emotions in general, and review the literature relating to the occurrence of hypomania associated with structural disease of the nervous system.

NEUROLOGY 1996;47: 1374-1378







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