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Neurology, Vol 48, Issue 4 1090-1093, Copyright © 1997 by American Academy of Neurology

ARTICLES

Human cortical plasticity: functional recovery with mirror movements

AC Nirkko, KM Rosler, C Ozdoba, O Heid, G Schroth and CW Hess
Department of Neurology, University Hospital, Bern, Switzerland.

Cortical plasticity of the human brain permits functional recovery after brain injury even in the absence of neuronal recovery. We report the combined evaluation, including electrophysiology and functional magnetic resonance imaging, of the pattern of cortical and cerebellar reorganization, in a patient with mirror movements as a sequel of perinatal unilateral brain injury. Recovery resulted in motor control by the healthy hemisphere using direct ipsilateral corticospinal projections and the contralateral cerebellum.


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