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NEUROLOGY 1997;49:207-212
© 1997 American Academy of Neurology

Peripheral neuropathy in children with HIV infection

M. K. Floeter, MD, PhD, L. A. Civitello, MD, C. R. Everett, MD, J. Dambrosia, PhD and C. A. Luciano, MD

From the EMG Section (Drs. Floeter and Luciano), NINDS, and the Pediatric Branch (Dr. Civitello), National Cancer Institute, NIH, Bethesda, MD; Children's National Medical Center (Dr. Civitello), Washington, DC; Biometry and Field Studies Branch (Dr. Dambrosia), NINDS, NIH, Bethesda, MD; and the Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN.

Address correspondence and reprint requests to Dr Floeter, EMG Laboratory, NINDS, NIH, Bld. 10 Room 5C101, 10 Center Drive MSC 1404, Bethesda, MD 20892.

Peripheral neuropathy is infrequently reported in children with HIV infection, but may be underrecognized. To provide a better understanding of the patterns of peripheral neuropathy in these children, we surveyed the charts of 50 children with HIV infection referred to the EMG laboratory at the National Institutes of Health for evaluation of suspected peripheral neuropathy. Twelve children had an abnormal nerve conduction study. The findings suggested a distal sensory or sensorimotor axonal neuropathy in seven children, median nerve compression at the carpal tunnel in three, a demyelinating neuropathy in one child, and a lumbosacral polyradiculopathy in one adolescent. Distal symmetric polyneuropathy occurred mostly in older-aged children.

Received January 18, 1996. Accepted in final form January 17, 1997.




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