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NEUROLOGY 1997;49:870-871
© 1997 American Academy of Neurology

Guillain-Barré and virus-associated hemophagocytic syndromes contracted simultaneously following Epstein-Barr viral infection

M. Kaneko, MD, S. Kuwabara, MD, A. Hatakeyama, MD, T. Fukutake, MD and T. Hattori, MD

From the Department of Neurology, School of Medicine, Chiba University, Chiba, Japan.

Address correspondence and reprint requests to Dr. Masaru Kaneko, Department of Neurology, School of Medicine, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba 260, Japan.

The virus-associated hemophagocytic syndrome (VAHS) is a lymphoproliferative disorder induced by viral infection. The peripheral nervous system is rarely involved in this syndrome and, when reported, the involvement has been axonal in nature. This paper presents a case of Guillain-Barré syndrome accompanied by VAHS subsequent to Epstein-Barr virus infection. The patient's condition improved following treatment with intravenous immunoglobulin infusion and high-dose corticosteroids.


Received September 26, 1996. Accepted in final form March 1, 1997.







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