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Gabapentin for familial paroxysmal dystonic choreoathetosis

From the Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX.

Address correspondence and reprint requests to Dr. Robert S. Chudnow, Department of Neurology, UT Southwestern Medical Center, 1935 Motor Street, Dallas, TX 75235-7794.

We present a 4-year-old girl with stereotyped episodes of inability to speak and dystonic posturing of the face and extremities lasting 20 minutes. An older brother and mother had similar spells in childhood. Routine and video-EEG during events were normal. The diagnosis was non-kinesigenic paroxysmal dystonic choreoathetosis since the episodes were not exacerbated by movement. Gabapentin 10 mg/kg/d eliminated most attacks.

Received February 26, 1997. Accepted in final form May 12, 1997.

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