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NEUROLOGY 1998;50:642-644
© 1998 American Academy of Neurology

Is videopupillography useful in the diagnosis of Alzheimer's disease?

E. Ferrario, MD, M. Molaschi, MD, L. Villa, MD, O. Varetto, MD, C. Bogetto, MD and R. Nuzzi, MD

From the Department of Geriatric Medicine (Drs. Ferrario, Molaschi, Villa, and Varetto) and the Institute of Ophthalmology (Drs. Bogetto and Nuzzi), University of Torino, Italy.

Address correspondence and reprint requests to Dr. Ermanno Ferrario, Department of Geriatric Medicine, University of Torino, Ospedale S. Giovanni Battista, Corso Bramante, 88, Torino, Italy.

Patients with Alzheimer's disease (AD) reportedly exhibit greater pupillary dilation than healthy subjects in response to tropicamide. By means of videopupillography, we have found that the average basal pupillary diameter was greater in AD patients than in normal controls and that there is an inverse relationship between the average pupillary diameter and the maximal dilation obtained following tropicamide application in both groups. Pupillary response to tropicamide and videopupillography do not distinguish between Alzheimer's patients and controls.

Presented in part at The Lancet Conference, Edinburgh, U.K., April 25-26, 1996.

Received April 10, 1997. Accepted in final form November 12, 1997.




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[Full Text] [PDF]

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 NeurologyHome page
J. Verghese, E. Ferrario, M. Molaschi, L. Villa, O. Varetto, C. Bogetto, and R. Nuzzi
Is videopupillography useful in diagnosing Alzheimer's disease?
Neurology, February 1, 1999; 52(3): 673 - 673.
[Full Text]


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