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Prevalence of dementia in Chinese elderly in Hong Kong

From the Department of Psychiatry (Drs. Chiu, Lam, Law, and Chung, and T. Leung and H.H.L. Fung) and the Centre for Clinical Trials and Epidemiological Research (Dr. Lau), Chinese University of Hong Kong; the Department of Social Work and Social Administration (Dr. Chi), University of Hong Kong; the Castle Peak Hospital (Dr. Li), Hong Kong; the Department of Radiology (Dr. Kan), Prince of Wales Hospital, Shatin, Hong Kong; and the Shatin Hospital (Dr. Lum and J. Ng), Shatin, Hong Kong.

Address correspondence and reprint requests to Dr. Helen F.K. Chiu, Department of Psychiatry, Prince of Wales Hospital, Shatin, Hong Kong.

This study examines the prevalence of dementia in elderly Chinese aged 70 years and older in Hong Kong using a two-phase design. In phase 1, 1,034 elderly were interviewed with the Cantonese version of the Mini-Mental State Examination. Those who scored below the cutoff points and a subsample of those with scores in the normal range were interviewed in phase 2 to identify those with dementia. The overall weighted prevalence of dementia in our subjects was 6.1 ± 0.7%, which is at the lower end of the range of rates reported in whites. Alzheimer's disease (AD) accounted for 64.6% and vascular dementia, 29.3%. Our results, together with previous studies in Chinese populations, suggest that the rates of AD in Chinese are low compared with those in whites. Substantial differences are possible in the epidemiology of dementia across cultures related to interactions of genetic and environmental factors.

Supported in part by a grant from Parke-Davis.

Received February 11, 1997. Accepted in final form October 29, 1997.

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