HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Boatman, D. Articles by Gordon, B. Search for Related Content PubMed PubMed Citation Articles by Boatman, D. Articles by Gordon, B.

Right hemisphere speech perception revealed by amobarbital injection and electrical interference

From the Departments of Neurology (Drs. Boatman, Hart, Lesser, Anderson, and Gordon), Otolaryngology (Dr. Boatman), Neurosurgery (Dr. Lesser), Psychiatry (Dr. Honeycutt), Cognitive Science (Drs. Boatman, Hart, and Gordon), Biostatistics (D. Miglioretti), and the Krieger Mind/Brain Institute(Drs. Boatman, Hart, Lesser, and Gordon), The Johns Hopkins University, Baltimore, MD.

Address correspondence and reprint requests to Dr. Dana Boatman, Department of Neurology, The Johns Hopkins School of Medicine, 600 North Wolfe Street/Meyer 222, Baltimore, MD 21287-7222.

Objective: To investigate the right hemispheric speech perception capabilities of an adult right-handed patient with seizures.

Methods: Consecutive, unilateral, intracarotid sodium amobarbital injections and left hemispheric electrical interference mapping were used to determine lateralization and localization of speech perception, measured as syllable discrimination.

Results: Syllable discrimination remained intact after left and right intracarotid sodium amobarbital injections. Language otherwise strongly lateralized to the left hemisphere. Despite evidence of bilateral speech perception capabilities, electrical interference testing in the left posterior temporal lobe impaired syllable discrimination.

Conclusions: The results suggest a functionally symmetric, parallel system in the adult brain with preferential use of left hemispheric pathways for speech perception.

Supported by grants from The Epilepsy Foundation of America, NIH-NIDCD(R29-DC03081), NIH-NINDS (RO1-NS26553, RO1-NS29973), and the Seaver Foundation.

Received July 22, 1997. Accepted in final form April 24, 1998.

This article has been cited by other articles:

				D. Boatman, E. P. Vining, J. Freeman, and B. Carson Auditory Processing Studied Prospectively in Two Hemidecorticectomy Patients J Child Neurol, March 1, 2003; 18(3): 228 - 232. [Abstract] [PDF]

				L. Hertz-Pannier, C. Chiron, I. Jambaque, V. Renaux-Kieffer, P.-F. V. d. Moortele, O. Delalande, M. Fohlen, F. Brunelle, and D. L. Bihan Late plasticity for language in a child's non-dominant hemisphere: A pre- and post-surgery fMRI study Brain, February 1, 2002; 125(2): 361 - 372. [Abstract] [Full Text] [PDF]

				S. Knecht, B. Drager, A. Floel, H. Lohmann, C. Breitenstein, M. Deppe, H. Henningsen, and E.-B. Ringelstein Behavioural relevance of atypical language lateralization in healthy subjects Brain, August 1, 2001; 124(8): 1657 - 1665. [Abstract] [Full Text] [PDF]

				D. Boatman and G. Krauss Language lateralisation and early right ear deafness: was Wernicke right? J. Neurol. Neurosurg. Psychiatry, October 1, 2000; 69(4): 538 - 540. [Abstract] [Full Text] [PDF]

				D. Boatman, B. Gordon, J. Hart, O. Selnes, D. Miglioretti, and F. Lenz Transcortical sensory aphasia: revisited and revised Brain, August 1, 2000; 123(8): 1634 - 1642. [Abstract] [Full Text] [PDF]