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NEUROLOGY 1998;51:1207-1209
© 1998 American Academy of Neurology

Right-side neglect in Alzheimer's disease

P. Bartolomeo, MD, PhD, G. Dalla Barba, MD, PhD, M.-F. Boissé, MA, A.-C. Bachoud-Lévi, MD, J.-D. Degos, MD and F. Boller, MD, PhD

From the INSERM Unit 324 (Drs. Bartolomeo, Boissé, Boller, and Dalla Barba), Paris; LSCP, EHESS, CNRS, Paris (Dr. Bachoud-Lévi); and the Neuroscience Department (Drs. Bachoud-Lévi, Bartolomeo, Dalla Barba, and Degos), Hôpital Henri-Mondor, Créteil, France.

Address correspondence and reprint requests to Dr. Paolo Bartolomeo, INSERM Unit 324, Centre Paul Broca, 2ter rue d'Alésia, F-75014 Paris, France.

Unilateral neglect-the inability to pay attention to events occurring on one side of space-usually occurs for left-side events after focal right-hemisphere damage. We report a 73-year-old woman with probable AD and no evidence of focal brain lesions who showed signs of right-side neglect and extinction. Neglect was more severe after 1 year. Neuroimaging techniques demonstrated an asymmetry of cortical involvement, with cortical atrophy and hypoperfusion predominant in the left posterior regions. Unilateral neglect should be assessed systematically in AD.

Supported by a grant from the France Alzheimer Association to Dr. Bartolomeo.

Received March 9, 1998. Accepted in final form June 18, 1998.




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