HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Silber, E. Articles by Saffer, D. Search for Related Content PubMed PubMed Citation Articles by Silber, E. Articles by Saffer, D.

Dual infective pathology in patients with cryptococcal meningitis

From the Department of Neurology (Drs. Silber and Saffer), Baragwanath Hospital and University of the Witwatersrand, Johannesburg, South Africa; Department of Neurology (Dr. Silber), Guy's Hospital, United Medical and Dental School, London, UK; Department of Community Health (Dr. Sonnenberg), University of the Witwatersrand; and Department of Medical Microbiology (Dr. Koornhof), South African Institute for Medical Research and University of the Witwatersrand, Johannesburg; and the MRC AIDS Research Unit (Dr. Morris), National Institute for Virology, Johannesburg, South Africa.

Address correspondence and reprint requests to Dr. Elli Silber, Department of Neurology, Guy's Medical School, London Bridge, London, SE1 9RT, UK.

Coinfection of the nervous system by two distinct nonviral organisms is uncommon and often undiagnosed. Medical teaching emphasizes that a single pathologic process should be sought; however, in the presence of severe immunocompromise this approach may not hold true. We describe seven HIV-1 seropositive patients with cryptococcal meningitis, three of whom had a proven nervous system infection with a second organism: concurrent tuberculous meningitis, a tuberculoma, and the first documented case of cryptococcal meningitis and neurosyphilis.

Dr. Sonnenberg's post was funded by the Epidemiology Research Unit, Department of Health and Gold Fields of South Africa.

Received March 20, 1998. Accepted in final form May 21, 1998.

This article has been cited by other articles:

				D Rawat, M R Capoor, D Nair, M Deb, and P Aggarwal Concomitant TB and cryptococcosis in HIV-infected patients Trop Doct, October 1, 2008; 38(4): 251 - 252. [Abstract] [Full Text] [PDF]

				M. Modi, A. Mochan, and G. Modi Management of HIV-associated focal brain lesions in developing countries QJM, July 1, 2004; 97(7): 413 - 421. [Abstract] [Full Text] [PDF]