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Neurology 1999;52:172
© 1999 American Academy of Neurology


Brief Communications

Normalization of creatine kinase level during arthritis in a patient with Becker muscular dystrophy

Yoshihiro Maegaki, MD, Kaeko Ogura, MD, Yukinori Maeoka, MD and Kenzo Takeshita, MD

From the Division of Child Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan.

Address correspondence and reprint requests to Dr. Yoshihiro Maegaki, Division of Child Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36-1 Nishi-Machi, Yonago 683-8504, Japan.

A patient with Becker muscular dystrophy had transient arthritis. During the active illness his serum creatine kinase (CK) level normalized and serum levels of soluble interleukin 2 (IL-2) receptor, IL-6, IL-1 receptor antagonist, and soluble tumor necrosis factor receptor 2 were elevated. CK increased to his usual levels after arthritis remission whereas the levels of inflammatory cytokines and their inhibitors decreased.




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