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Neurology 1999;52:409
© 1999 American Academy of Neurology


Brief Communications

Predictive value of the intracarotid amobarbital test in bihemispheric seizure onset

J. M. Swearer, PhD, K. J. Kane, MA, C. A. Phillips, MD, J. P. Weaver, MD, T. D. Anderson, BA and M. S. Lavoie, PhD

From the Departments of Neurology (Drs. Swearer, Phillips, and Lavoie, and K.J. Kane and T.D. Anderson) and Neurosurgery (Dr. Weaver), University of Massachusetts Medical Center, Worcester, MA.

Address correspondence and reprint requests to Dr. Joan M. Swearer, Department of Neurology, University of Massachusetts Medical Center, 55 Lake Avenue North, Worcester, MA 01655.

The intracarotid amobarbital test (IAT) is used to lateralize language function and assess hemispheric memory. In this study 23 nonlesional epileptic patients were evaluated. The magnitude of the difference in IAT scores between the two hemispheres was significantly greater in the patients whose seizures lateralized on scalp or intracranial EEG than in patients with bihemispheric seizure onset. This suggests that the IAT is useful not only in predicting lateralized seizure focus, but bihemispheric onset as well.




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S. A. Baxendale, P. J. Thompson, and J. S. Duncan
Evidence-Based Practice: A Reevaluation of the Intracarotid Amobarbital Procedure (Wada Test)
Arch Neurol, June 1, 2008; 65(6): 841 - 845.
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