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Neurology 1999;52:417
© 1999 American Academy of Neurology
Brief Communications

Abolished tilt suppression of the vestibulo-ocular reflex caused by a selective uvulo-nodular lesion

G. Wiest, MD, L. Deecke, MD, S. Trattnig, MD and C. Mueller, MD

From the Department of Neurology (Drs. Wiest, Deecke, and Mueller) and the MRI Institute, Department of Radiology (Dr. Trattnig), University of Vienna, Austria.

Address correspondence and reprint requests to Dr. Gerald Wiest, Department of Clinical Neurology, University Clinic of Neurology, Währingergürtel 18-20, A-1090 Vienna, Austria.

Within the cerebellum several structures are considered to modulate the function of the vestibulo-ocular reflex (VOR). The nodulus and uvula have been implicated with the low-frequency components of the VOR, which are mediated by the velocity storage system. We report a patient with a selective lesion of the nodulus and ventral uvula. The findings suggest that nodulus and uvula normally exert an inhibitory effect on the velocity storage mechanism.




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