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Control of primary angiitis of the CNS associated with cerebral amyloid angiopathy by cyclophosphamide alone

From the Departments of Neurology (Dr. Fountain) and Pathology (Neuropathology) (Dr. Lopes), University of Virginia Health Sciences Center, Charlottesville, VA.

Address correspondence and reprint requests to Dr. Nathan B. Fountain, Department of Neurology, Box 394, University of Virginia Health Sciences Center, Charlottesville, VA 22908.

Corticosteroids combined with cyclophosphamide are currently recommended for primary angiitis of the CNS. The authors report a 71-year-old man with primary angiitis of the CNS and amyloid angiopathy who responded to cyclophosphamide without steroids, suggesting that corticosteroids may not be needed in all cases of primary angiitis of the CNS.

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