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Arm levitation in progressive supranuclear palsy

From the Division of Neurology (Dr. Barclay), University of Ottawa; and the Department of Pathology (Dr. Bergeron) and Division of Neurology (Dr. Lang), University of Toronto, Canada. Dr. Anthony Lang is partially supported by a Center of Excellence Grant from the National Parkinson Foundation.

Address correspondence and reprint requests to Dr. Anthony E. Lang, The Toronto Hospital, Western Division, 399 Bathurst St., MP11, Toronto, Ontario, Canada M5T 2S8.

Spontaneous arm levitation (SAL) is well-recognized in cortical–basal ganglionic degeneration, but not in other neurodegenerative diseases. We report six cases of progressive supranuclear palsy (PSP) with SAL. Pathologic examination in four revealed the classic features of PSP with additional areas of focal cortical degeneration. We conclude that SAL can occur in PSP and its occurrence may be a marker of cortical degeneration.

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