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Neurology 1999;52:1503
© 1999 American Academy of Neurology
Brief Communications

Contrast agent neurotoxicity presenting as subarachnoid hemorrhage

Stephen Sharp, MD, Jeffrey Stone, MD and Robert Beach, MD, PhD

From the Departments of Neurology and Neuroradiology, University of North Carolina at Chapel Hill, NC.

Address correspondence and reprint requests to Dr. Stephen Sharp, CB 7025, 751 Clinical Sciences Building, Department of Neurology, University of North Carolina–Chapel Hill, Chapel Hill, NC 27599.

A patient developed signs, symptoms, and radiologic findings compatible with acute subarachnoid hemorrhage after receiving a large dose of heparin and intravascular contrast medium for coronary angiography and stent placement. Subsequent CT indicated the subarachnoid enhancement was due to contrast. Neurotoxicity from contrast agents is well-known, however this is an unusual report of toxicity mimicking subarachnoid hemorrhage clinically and radiologically.




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