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Corneomandibular reflex in ALS

From the Division of Neurology, Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.

Address correspondence and reprint requests to Dr. B. Okuda, Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishimoniya 663-8501, Japan.

To clarify the diagnostic value of corneomandibular reflex (CMR) in ALS, the authors examined the prevalence of CMR and other pathologic reflexes in 42 patients with ALS and 110 patients with stroke. A total of 30 of 42 ALS patients had positive CMR. Compared with the patients with hemiparesis or pseudobulbar palsy after stroke, the ALS patients showed a significantly higher frequency of CMR but no other pathologic reflexes. CMR is a sensitive indicator of upper motor neuron involvement in ALS.

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