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Neurology 1999;52:1750
© 1999 American Academy of Neurology
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Applications of diffusion–perfusion magnetic resonance imaging in acute ischemic stroke

Marc Fisher, MD and Gregory W. Albers, MD

From the Department of Neurology (Dr. Fisher), University of Massachusetts Medical School, Worcester, MA; and Stanford University Medical Center (Dr. Albers), CA.

Address correspondence and reprint requests to Dr. Marc Fisher, UMASS/Memorial Health Care, 119 Belmont Street, Worcester, MA 01605.

Article Abstract

Diffusion-weighted imaging (DWI) and perfusion imaging (PI) are two new magnetic resonance technologies that are becoming increasingly available for evaluation of acute ischemic stroke patients. DWI provides information about the location of acute focal ischemic brain injury at early time points and PI can document the presence of disturbances in microcirculatory perfusion. DWI and PI are now being used in clinical practice and in clinical trials of potential acute stroke therapies to assess their utility. In the future, DWI and PI may aid in the development of effective acute stroke therapies and help identify which stroke patients are most likely to benefit from specific agents.




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