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Neurology 1999;53:1342
© 1999 American Academy of Neurology
Brief Communications

Autopsy patterns for Parkinson’s disease and related disorders in Olmsted County, Minnesota

D. M. Maraganore, MD, D. W. Anderson, PhD, J. H. Bower, MD, S. K. McDonnell, MS and W. A. Rocca, MD, MPH

From the Departments of Neurology (Drs. Maraganore, Bower, and Rocca) and Health Sciences Research (S.K. McDonnell and Dr. Rocca), Mayo Clinic and Mayo Foundation, Rochester, MN; and Biometry and Field Studies Branch (Dr. Anderson), National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD.

Address correspondence and reprint requests to Dr. D.M. Maraganore, Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905; e-mail: dmaraganore{at}mayo.edu

Using a records-linkage system, we determined the frequency and distribution of brain autopsies in residents of Olmsted County, Minnesota, in whom parkinsonism developed during 1976 through 1990. Of the 364 incident cases identified, 235 patients were deceased at the time of record abstraction. The overall autopsy rate was low (23%). Diagnostic certainty (for PD), diagnostic type (PD versus other parkinsonism), sex, age at death, and location at death were important selection factors for autopsy.

Key words: Autopsy patterns—PD.




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