| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
From the Department of Nuclear Medicine (KME) (Dr. Mottaghy), Research Center, Juelich, Germany; the Departments of Neurology and Neurolinguistics (Drs. Hungs, Brügmann, Boroojerdi, Foltys, Huber, and Töpper, and R. Sparing), University Hospital, RWTH Aachen, Germany; and the Human Cortical Physiology Unit (Dr. Boroojerdi), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Address correspondence and reprint requests to Dr. Felix M. Mottaghy, Department of Nuclear Medicine (KME), Research Center Juelich, 52426 Juelich, Germany.
OBJECTIVE: To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on picture naming.
BACKGROUND: Previous studies have shown that rTMS disrupts ongoing speech processes when delivered over frontal or parietal areas of the dominant hemisphere.
METHODS: In 15 healthy right-handed male individuals, rTMS trains of 20 Hz with a duration of 2 seconds and an intensity of 55% of maximum stimulator output were delivered either to Wernicke’s area, to the right-hemisphere homologue of Wernicke’s area, to Broca’s area, or to the primary visual cortex. Twenty black-and-white line drawings, which the individuals had to name as quickly as possible, were shown immediately after the completion of rTMS and again 2 minutes later.
RESULTS: Immediately after the end of a train over Wernicke’s area a shortening of naming latency was observed compared with naming without rTMS (p < 0.001). No significant effects on picture naming were observed 2 minutes later or at any time after stimulation of the right-hemisphere homologues of Wernicke’s area, Broca’s area, or the visual cortex.
CONCLUSION: Repetitive transcranial magnetic stimulation over Wernicke’s area leads to a brief facilitation of picture naming by shortening linguistic processing time.
Key words: Repetitive transcranial magnetic stimulation—Speech-related areas—Reaction time—Linguistic.
This article has been cited by other articles:
|
|
 |
|
  A. Floel, N. Rosser, O. Michka, S. Knecht, and C. Breitenstein Noninvasive Brain Stimulation Improves Language Learning J. Cogn. Neurosci., August 1, 2008; 20(8): 1415 - 1422. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. R. Buchsbaum and M. D'Esposito The search for the phonological store: from loop to convolution. J. Cogn. Neurosci., May 1, 2008; 20(5): 762 - 778. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Andoh, E. Artiges, C. Pallier, D. Riviere, J.-F. Mangin, M.-L. Paillere-Martinot, and J.-L. Martinot Priming Frequencies of Transcranial Magnetic Stimulation over Wernicke's Area Modulate Word Detection Cereb Cortex, January 1, 2008; 18(1): 210 - 216. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Sole-Padulles, D. Bartres-Faz, C. Junque, I. C. Clemente, J. L. Molinuevo, N. Bargallo, J. Sanchez-Aldeguer, B. Bosch, C. Falcon, and J. Valls-Sole Repetitive Transcranial Magnetic Stimulation Effects on Brain Function and Cognition among Elders with Memory Dysfunction. A Randomized Sham-Controlled Study Cereb Cortex, October 1, 2006; 16(10): 1487 - 1493. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. A. Karim, A. Schuler, Y. L. Hegner, E. Friedel, and B. Godde Facilitating effect of 15-Hz repetitive transcranial magnetic stimulation on tactile perceptual learning. J. Cogn. Neurosci., September 1, 2006; 18(9): 1577 - 1585. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Ueki, T. Mima, K. Nakamura, T. Oga, H. Shibasaki, T. Nagamine, and H. Fukuyama Transient Functional Suppression and Facilitation of Japanese Ideogram Writing Induced by Repetitive Transcranial Magnetic Stimulation of Posterior Inferior Temporal Cortex. J. Neurosci., August 15, 2006; 26(33): 8523 - 8530. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Lewald, I. G. Meister, J. Weidemann, and R. Topper Involvement of the Superior Temporal Cortex and the Occipital Cortex in Spatial Hearing: Evidence from Repetitive Transcranial Magnetic Stimulation J. Cogn. Neurosci., June 1, 2004; 16(5): 828 - 838. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Robertson, H. Theoret, and A. Pascual-Leone Studies in Cognition: The Problems Solved and Created by Transcranial Magnetic Stimulation J. Cogn. Neurosci., October 1, 2003; 15(7): 948 - 960. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Cornelissen, M. Laine, A. Tarkiainen, T. Jarvensivu, N. Martin, and R. Salmelin Adult Brain Plasticity Elicited by Anomia Treatment J. Cogn. Neurosci., April 1, 2003; 15(3): 444 - 461. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Floel, C. Breitenstein, S. Knecht, S.F. Cappa, M. Sandrini, P.M. Rossini, K. Sosta, and C. Miniussi The role of the left frontal lobe in action naming: rTMS evidence Neurology, March 25, 2003; 60(6): 1052 - 1052. [Full Text] [PDF]
|
|
|
|
 |
|
 Z. J. Daskalakis, B. K. Christensen, P. B. Fitzgerald, and R. Chen Transcranial Magnetic Stimulation: A New Investigational and Treatment Tool in Psychiatry J Neuropsychiatry Clin Neurosci, November 1, 2002; 14(4): 406 - 415. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. F. Cappa, M. Sandrini, P. M. Rossini, K. Sosta, and C. Miniussi The role of the left frontal lobe in action naming: rTMS evidence Neurology, September 10, 2002; 59(5): 720 - 723. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Boroojerdi, M. Phipps, L. Kopylev, C.M. Wharton, L.G. Cohen, and J. Grafman Enhancing analogic reasoning with rTMS over the left prefrontal cortex Neurology, February 27, 2001; 56(4): 526 - 528. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
