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Vasogenic edema on MELAS: A serial study with diffusion-weighted MR imaging

From the Second Department of Internal Medicine (Drs. Yoneda, Fujii, and Kuriyama), and the Department of Radiology (Drs. Maeda and Kimura), Fukui Medical University, Fukui, Japan; and the Department of Pediatrics (Dr. Katayama), Fukui Pref. Saiseikai Hospital, Fukui, Japan.

Address correspondence and reprint requests to Dr. Makoto Yoneda, the Second Department of Internal Medicine, Fukui Medical University, Fukui 910-1104, Japan; e-mail: myoneda{at}fmsrsa.fukui-med.ac.jp

The authors performed a serial study of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like syndrome (MELAS) who presented with diffusion-weighted MRI (DWI). DWI demonstrated a higher apparent diffusion coefficient in the lesion than in the control region during the acute stage of stroke. Vasogenic edema is present in stroke-like episodes in MELAS.

Key words: MELAS—Stroke-like episodes—MRI—Apparent diffusion coefficient maps.

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