Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Melberg, A.
Right arrow Articles by Raininko, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Melberg, A.
Right arrow Articles by Raininko, R.
Neurology 1999;53:2190
© 1999 American Academy of Neurology
Brief Communications

Neuroimaging study in autosomal dominant cerebellar ataxia, deafness, and narcolepsy

A. Melberg, MD, PhD, N. Dahl, MD, PhD, J. Hetta, MD, PhD, S. Valind, MD, PhD, I. Nennesmo, MD, PhD, P. O. Lundberg, MD, PhD and R. Raininko, MD, PhD

From the Departments of Neuroscience, Neurology (Drs. Melberg and Lundberg), Psychiatry (Dr. Hetta), Pathology and Genetics, Clinical Genetics (Dr. Dahl), Oncology, Radiology, and Clinical Immunology, Radiology (Dr. Raininko), Uppsala University Hospital, Uppsala University PET Center (Dr. Valind), Uppsala, and Division of Pathology (Dr. Nennesmo), Huddinge Hospital, Karolinska Institute, Stockholm, Sweden.

Address correspondence and reprint requests to Dr. Atle Melberg, Department of Neuroscience, Neurology, University Hospital, S-751 85 Uppsala, Sweden; e-mail: atle.melberg{at}neurologi.uu.se

Four patients affected with autosomal dominant cerebellar ataxia, deafness, and narcolepsy underwent brain CT and MRI. Radiologic findings were supratentorial atrophy (more pronounced than infratentorial atrophy), pronounced dilatation of the third ventricle, low T2 signal intensity in the basal ganglia, loss of cerebral cortex–white matter differentiation, and periventricular high-signal rims. 2-[18F]Fluoro-2-deoxy-D-glucose PET was done with one patient, without specific findings. Genetic analyses excluded SCA-1, SCA-2, SCA-3, SCA-6, SCA-7, DRPLA, and huntingtin gene mutations.

Key words: Hereditary—Cerebellar ataxia—Deafness—Narcolepsy—CT—MRI—PET—Genetics.




This article has been cited by other articles:


Home page
 Am. J. Neuroradiol.Home page
M.-H. Martin, J.-P. Bouchard, M. Sylvain, O. St-Onge, and S. Truchon
Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay: A Report of MR Imaging in 5 Patients
AJNR Am. J. Neuroradiol., September 1, 2007; 28(8): 1606 - 1608.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
T. J. Young and M. H. Silber
Hypersomnias of central origin.
Chest, September 1, 2006; 130(3): 913 - 920.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
M. C. Kruit, L. J. Launer, M. D. Ferrari, and M. A. van Buchem
Infarcts in the posterior circulation territory in migraine. The population-based MRI CAMERA study
Brain, September 1, 2005; 128(9): 2068 - 2077.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
T.E. Scammell, S. Nishino, E. Mignot, and C.B. Saper
Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke
Neurology, June 26, 2001; 56(12): 1751 - 1753.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1999 by AAN Enterprises, Inc.