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From the Neurodegenerative Disorders Centre, UBC Hospital, Vancouver, BC, Canada.
Address correspondence and reprint requests to Dr. J.K.C. Tsui, Neurodegenerative Disorders Centre, Vancouver Hospital and Health Sciences Centre, Purdy Pavilion, 2221 Wesbrook Mall, Vancouver, BC, Canada V6T 2B5; e-mail: jtsui{at}interchange.ubc.ca
The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease.
Key words: Botulinum toxin A—Saliva—Drooling—PD
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