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Neurology 2000;54:1994-1997
© 2000 American Academy of Neurology
Brief Communications

Self-injection ictal SPECT during partial seizures

W. Van Paesschen, MRCP, PhD, P. Dupont, PhD, B. Van Heerden, MD, H. Vanbilloen, PhD, L. Mesotten, MD, A. Maes, MD, PhD, G. Van Driel and L. Mortelmans, MD, PhD

From the Departments of Neurology (Dr. Van Paesschen and G. Van Driel) and Nuclear Medicine (Drs. Dupont, Van Heerden, Vanbilloen, Mesotten, Maes, and Mortelmans), University Hospital Gasthuisberg, Leuven, Belgium; and the Department of Nuclear Medicine (Dr. Van Heerden), University of Stellenbosch and Tygerberg Hospital, Tygerberg, South Africa.

Address correspondence and reprint requests to Dr. W. Van Paesschen, University Hospital Gasthuisberg, Department of Neurology, 49 Herestraat, 3000 Leuven, Belgium.

The authors compared ictal SPECT injection performed by medical personnel with self-injection ictal SPECT in six patients with refractory temporal lobe epilepsy. Self-injection was safe and started faster. Self-injection subtraction ictal SPECT coregistered to MRI (SISCOM) was localizing in three patients who had a complex partial seizure, but only one of three patients who had a simple partial seizure, which may limit its usefulness in clinical practice. The localizing information of self-injection was better in three patients, and obviated the need for depth-EEG studies in one patient.

Key words: Ictal SPECT—Self-injection subtraction ictal SPECT coregistered to MRI—Self-injection—Epilepsy—99mTc-ECD.




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