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Neurology 2000;54:2161-2163
© 2000 American Academy of Neurology
Brief Communications

Gabapentin’s effects on hot flashes and hypothermia

Thomas J. Guttuso, Jr., MD

From the Department of Neurology, University of Rochester, NY.

Address correspondence and reprint requests to Dr. Thomas Guttuso, Department of Neurology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642; thomas_guttuso{at}urmc.rochester.edu

The author describes six cases in which gabapentin treatment reduced the frequency of hot flashes. In addition, gabapentin treatment enhanced the frequency of hypothermic episodes in a separate patient with known hypothalamic dysfunction. Gabapentin may act directly upon temperature regulatory centers.

Key words: Gabapentin—Hot flashes—Hypothermia.




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