Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gwinn-Hardy, K. A.
Right arrow Articles by Farrer, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gwinn-Hardy, K. A.
Right arrow Articles by Farrer, M.
Neurology 2000;54:504
© 2000 American Academy of Neurology
Brief Communications

A kindred with Parkinson’s disease not showing genetic linkage to established loci

K. A. Gwinn-Hardy, MD, R. Crook, BSc, S. Lincoln, BSc, C. H. Adler, MD, PhD, J. N. Caviness, MD, J. Hardy, PhD and M. Farrer, PhD

From the Mayo Clinic Jacksonville (Drs. Gwinn-Hardy, Hardy, and Farrer, and R. Crook and S. Lincoln), Jacksonville, FL; and the Mayo Clinic Scottsdale (Drs. Adler and Caviness), Scottsdale, AZ.

Address correspondence and reprint requests to Dr. Gwinn-Hardy, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL 32224.

We describe a kindred with PD with an onset age from the fifth to the eighth decade. Genetic analysis indicated that the genetic defect in this family was unlikely to be in the {alpha}-synuclein, parkin, or tau genes, or to reside on chromosomes 2p or 4p.

Key words: Familial PD—Postural tremor—Linkage exclusion




This article has been cited by other articles:


Home page
 J. Neurol. Neurosurg. PsychiatryHome page
T Foltynie, S Sawcer, C Brayne, and R A Barker
The genetic basis of Parkinson's disease
J. Neurol. Neurosurg. Psychiatry, October 1, 2002; 73(4): 363 - 370.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
D. J. Nicholl, J. R. Vaughan, N. L. Khan, S. L. Ho, D. E. W. Aldous, S. Lincoln, M. Farrer, J. D. Gayton, M. B. Davis, P. Piccini, et al.
Two large British kindreds with familial Parkinson's disease: a clinico-pathological and genetic study
Brain, January 1, 2002; 125(1): 44 - 57.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Zhang, J. Gao, K. K. K. Chung, H. Huang, V. L. Dawson, and T. M. Dawson
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
PNAS, November 8, 2000; (2000) 240347797.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Zhang, J. Gao, K. K. K. Chung, H. Huang, V. L. Dawson, and T. M. Dawson
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
PNAS, November 21, 2000; 97(24): 13354 - 13359.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2000 by AAN Enterprises, Inc.