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Neurology 2000;54:759
© 2000 American Academy of Neurology
Brief Communications

Neurogenic stunned myocardium in Guillain–Barré syndrome

Richard Bernstein, MD, PhD, Stephan A. Mayer, MD and Anthony Magnano, MD

From the Division of Critical Care Neurology, Department of Neurology, Neurological Institute (Drs. Bernstein and Mayer); and the Division of Cardiology, Department of Medicine (Dr. Magnano), Columbia-Presbyterian Medical Center, New York, NY.

Address correspondence and reprint requests to Dr. Stephan A. Mayer, Division of Critical Care Neurology, Neurological Institute, 710 West 168th Street, Box 39, New York, NY 10032.

Neurogenic stunned myocardium (NSM), a syndrome of reversible left ventricular dysfunction best described after subarachnoid hemorrhage, has not been associated with peripheral neuropathy. We describe a woman with Guillain–Barré syndrome in whom a syndrome compatible with NSM developed in the setting of a physiologically documented increase in sympathetic cardiovascular tone. This case supports the presumed unifying role of excessive sympathetic nervous system activation in the pathogenesis of NSM.

Key words: Neurogenic stunned myocardium—Guillain–Barré syndrome—Electrocardiogram—Echocardiography




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