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Neurology 2000;54:978-980
© 2000 American Academy of Neurology
Brief Communications

Amnesic confabulatory syndrome after focal basal forebrain damage

Ritsuo Hashimoto, MD, Yasufumi Tanaka, MD and Imaharu Nakano, MD

From the Department of Neurology, Jichi Medical School, Tochigi, Japan.

Address correspondence and reprint requests to Dr. Ritsuo Hashimoto, Department of Neurology, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi, Tochigi 329-0498, Japan.

A 73-year-old woman developed amnesic confabulatory syndrome after a right focal basal forebrain hemorrhage. The confabulation, despite persistent antegrade amnesia, gradually subsided with improvement of the frontal executive function. The lesion appeared to disrupt connections of the medial and lateral limbic circuits important for memory. Simultaneous dysfunctioning of the two circuits involving the medial temporal and frontal lobes may be necessary for the development of this syndrome.

Key words: Basal forebrain—Amnesia—Confabulation—Hemorrhage




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