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From the Institute and Outpatient Department for Occupational, Social and Environmental Medicine (Drs. Letzel, Angerer, and Lehnert, and K. H. Schaller), University of Erlangen-Nuremberg, Erlangen; and the Neurological Hospital (Drs. Lang, Fuchs, and Neundörfer), University of Erlangen-Nuremberg, Erlangen, Germany.
Address correspondence and reprint requests to Dr. Stephan Letzel, Institut für Arbeits-, Sozial- und Umweltmedizin, Schillerstr. 25/29, D-91054 Erlangen, Germany; e-mail: stephan.letzel{at}rzmail.uni-erlangen.de
Two cross-sectional studies were conducted at a German aluminum (Al) powder plant to evaluate possible nervous system effects from occupational Al exposure. The investigation included biological monitoring, a neuropsychological test battery, and event-related P300 potentials. Neurophysiologic findings in workers chronically exposed to Al dust did not differ from nonAl-exposed controls from the same plant. The authors suggest that chronic exposure to Al dust, at the levels documented in this study, does not induce measurable cognitive decline.
Key words: AluminumToxicologyOccupational exposureNeuropsychological testingCognitive decline
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