| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
4 predicts incident AD in Japanese-American men: The Honolulu–Asia Aging Study
From the Epidemiology, Demography and Biometry Program (Drs. Havlik, Izmirlian, Brock, and Launer, and D. Foley) National Institute on Aging, National Institutes of Health, Bethesda, MD; the Honolulu-Asia Aging Study (Drs. Petrovitch, Masaki, Curb, and White), Kuakini Medical Center, Honolulu, HI; the Department of Veterans’ Affairs (Dr. Ross), Honolulu, HI; the Department of Medicine (Drs. Petrovitch, Ross, Masaki, Curb, and White) University of Hawaii, John A. Burns School of Medicine, Honolulu, HI; and the Joseph and Kathleen Bryan Alzheimer’s Disease Research Center, Department of Medicine (Neurology) (Dr. Saunders), Duke University Medical Center, Durham, NC.
Address correspondence and reprint requests to Dr. Richard Havlik, Epidemiology, Demography and Biometry Program, National Institute on Aging, Gateway Building Suite 3C-309, Bethesda, MD 20892; e-mail: havlikr{at}gw.nia.nih.gov
The authors assessed the 3-year incidence of dementia, including subtypes, in 2,603 Japanese-American men 71 to 93 years of age who were dementia free at baseline. There were 137 new cases of dementia according to the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition, revised, including 51 with a primary diagnosis of AD. The rates for all subtypes increased with age. Men with an APOE4 allele had a significantly increased risk of AD of 2.39 (95% CI, 1.07, 5.31), after adjusting for age and education. There was no significant relationship of APOE4 with other subtypes of dementia.
Key words: Dementia—Risk factors—Epidemiology
This article has been cited by other articles:
|
|
 |
|
  J. S. Saczynski, L. White, R. L. Peila, B. L. Rodriguez, and L. J. Launer The Relation between Apolipoprotein A-I and Dementia: The Honolulu-Asia Aging Study Am. J. Epidemiol., May 1, 2007; 165(9): 985 - 992. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Peila, L. R. White, K. Masaki, H. Petrovitch, and L. J. Launer Reducing the Risk of Dementia: Efficacy of Long-Term Treatment of Hypertension Stroke, May 1, 2006; 37(5): 1165 - 1170. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. S. Saczynski, L. A. Pfeifer, K. Masaki, E. S. C. Korf, D. Laurin, L. White, and L. J. Launer The Effect of Social Engagement on Incident Dementia: The Honolulu-Asia Aging Study Am. J. Epidemiol., March 1, 2006; 163(5): 433 - 440. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. H. Freitag, R. Peila, K. Masaki, H. Petrovitch, G. W. Ross, L. R. White, and L. J. Launer Midlife Pulse Pressure and Incidence of Dementia: The Honolulu-Asia Aging Study Stroke, January 1, 2006; 37(1): 33 - 37. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. White, B. J. Small, H. Petrovitch, G. W. Ross, K. Masaki, R. D. Abbott, J. Hardman, D. Davis, J. Nelson, and W. Markesbery Recent Clinical-Pathologic Research on the Causes of Dementia in Late Life: Update From the Honolulu-Asia Aging Study J Geriatr Psychiatry Neurol, December 1, 2005; 18(4): 224 - 227. [Abstract] [PDF]
|
|
|
|
 |
|
 R. Stewart, K. Masaki, Q.-L. Xue, R. Peila, H. Petrovitch, L. R. White, and L. J. Launer A 32-Year Prospective Study of Change in Body Weight and Incident Dementia: The Honolulu-Asia Aging Study Arch Neurol, January 1, 2005; 62(1): 55 - 60. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D. Abbott, L. R. White, G. W. Ross, K. H. Masaki, J. D. Curb, and H. Petrovitch Walking and Dementia in Physically Capable Elderly Men JAMA, September 22, 2004; 292(12): 1447 - 1453. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Peila, B. L. Rodriguez, L. R. White, and L. J. Launer Fasting insulin and incident dementia in an elderly population of Japanese-American men Neurology, July 27, 2004; 63(2): 228 - 233. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. S.C. Korf, L. R. White, P. Scheltens, and L. J. Launer Midlife Blood Pressure and the Risk of Hippocampal Atrophy: The Honolulu Asia Aging Study Hypertension, July 1, 2004; 44(1): 29 - 34. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Laurin, K. H. Masaki, D. J. Foley, L. R. White, and L. J. Launer Midlife Dietary Intake of Antioxidants and Risk of Late-Life Incident Dementia: The Honolulu-Asia Aging Study Am. J. Epidemiol., May 15, 2004; 159(10): 959 - 967. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Greenwood and R. Parasuraman Normal Genetic Variation, Cognition, and Aging Behav Cogn Neurosci Rev, December 1, 2003; 2(4): 278 - 306. [Abstract] [PDF]
|
|
|
|
|
|
W. A. Kukull, R. Higdon, J. D. Bowen, W. C. McCormick, L. Teri, G. D. Schellenberg, G. van Belle, L. Jolley, and E. B. Larson Dementia and Alzheimer Disease Incidence: A Prospective Cohort Study Arch Neurol, November 1, 2002; 59(11): 1737 - 1746. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Peila, B. L. Rodriguez, and L. J. Launer Type 2 Diabetes, APOE Gene, and the Risk for Dementia and Related Pathologies: The Honolulu-Asia Aging Study Diabetes, April 1, 2002; 51(4): 1256 - 1262. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Havlik, D. J. Foley, B. Sayer, K. Masaki, L. White, and L. J. Launer Variability in Midlife Systolic Blood Pressure Is Related to Late-Life Brain White Matter Lesions: The Honolulu-Asia Aging Study Stroke, January 1, 2002; 33(1): 26 - 30. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. J. Launer, L. R. White, H. Petrovitch, G. W. Ross, and J. D. Curb Cholesterol and neuropathologic markers of AD: A population-based autopsy study Neurology, October 23, 2001; 57(8): 1447 - 1452. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Foley, K. Masaki, L. White, S. Redline, E. Mignot, G. M. Murphy, Jr, and T. Young Relationship Between Apolipoprotein E {epsilon}4 and Sleep-Disordered Breathing at Different Ages JAMA, September 26, 2001; 286(12): 1447 - 1448. [Full Text] [PDF]
|
|
|
|
|
|
H. Petrovitch, L.R. White, G.W. Ross, S.C. Steinhorn, C.Y. Li, K.H. Masaki, D.G. Davis, J. Nelson, J. Hardman, J.D. Curb, et al. Accuracy of clinical criteria for AD in the Honolulu-Asia Aging Study, a population-based study Neurology, July 24, 2001; 57(2): 226 - 234. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
