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From the Human Cortical Physiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Address correspondence and reprint requests to Dr. Leonardo G. Cohen, Building 10, Room 5N 234, National Institutes of Health, 10 Center Drive, MSC 1428, Bethesda, MD 20892-1428; e-mail: lcohen{at}codon.nih.gov
The effects of low-frequency (1-Hz) repetitive transcranial magnetic stimulation on visual cortex excitability were investigated by measuring phosphene thresholds (PTs) and stimulus-response curves. Stimulation over the visual cortex led to significantly decreased visual cortex excitability, expressed as an increase in PT. The motor threshold of the hand muscles did not change, indicating the topographic specificity of this effect. This intervention may be useful in situations associated with a hyperexcitable visual cortex.
Key words: Visual cortex—Transcranial magnetic stimulation—Excitability
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