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From the Departments of Neurosurgery (Drs. Gruber, Bavinzski, and Czech), Neuroradiology (Dr. Nasel), Neurology (Dr. Lang), and Pediatrics (Dr. Kitzmüller), University of Vienna Medical School, Austria.
Address correspondence and reprint requests to Dr. Andreas Gruber, Department of Neurosurgery, University of Vienna Medical School, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
Local intra-arterial lysis using recombinant tissue plasminogen activator (rTPA) was performed in a 6 and 2/3-year-old patient with major cardioembolic ischemic stroke 48 hours after intracardiac surgery. Selective application of 2.5 mg rTPA (0.11 mg/kg body weight) resulted in recanalization of the occluded cerebral vasculature with good neurologic recovery.
Key words: Intra-arterial thrombolysis—Perioperative childhood cardioembolic stroke.
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