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From the Departments of Neurology (Drs. Kitagawa, Kikuchi, Sasaki, and Tashiro) and Neurosurgery (Drs. Murata and Sawamura), Hokkaido University of Medicine, and Sapporo Azabu Neurosurgical Hospital (Dr. Saito), Japan.
Address correspondence and reprint requests to Dr. Mayumi Kitagawa, Department of Neurology, Hokkaido University Graduate School of Medicine, North-14 West-5, Kita-ku, Sapporo 060-8638, Japan; e-mail: azbneuro{at}po.iijnet.or.jp
Proximal tremors are often refractory to nucleus ventrointermedius thalami thalamotomy. Subthalamotomy has been suggested to be effective for treatment of tremor, although this procedure is associated with considerable adverse effects, and has rarely been considered a suitable treatment modality. The authors demonstrate the efficacy and safety of subthalamic deep brain stimulation in two patients, one with a severe, refractory proximal essential tremor and one with tremor with dystonia.
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