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Neurology 2000;55:1904-1905
© 2000 American Academy of Neurology
Brief Communications

Induction of psychogenic nonepileptic seizures without placebo

S. R. Benbadis, MD;, K. Johnson;, K. Anthony, R.EEG.T;, G. Caines, R.EEG.T;, G. Hess, R.EEG.T;, C. Jackson, R.EEG.T;, F. L. Vale, MD; and and W. O. Tatum IV, DO

From the Comprehensive Epilepsy Program, University of South Florida College of Medicine; and Tampa General Healthcare, Tampa, FL.

Address correspondence and reprint requests to Dr. Selim R. Benbadis, Associate Professor, Departments of Neurology & Neurosurgery, 4 Columbia Drive, Suite 730, Tampa, FL 33606; e-mail: sbenbadi{at}hsc.usf.edu

The diagnosis of psychogenic nonepileptic seizures (PNES) can only be made with EEG-video monitoring. The authors describe a provocative technique without placebo. Patients with a clinical suspicion for PNES underwent an activation procedure using suggestion, hyperventilation, and photic stimulation. Of 19 inductions performed, 16 (84%) were successful in inducing the habitual episode. The authors’ technique had a sensitivity comparable to those using placebo (e.g., saline injection), but does not have disadvantages.




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