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Cytomegalovirus ventriculoencephalitis presenting as a Wernicke’s encephalopathy–like syndrome

From the Department of Neurology (Dr. Torgovnick), St. Vincent’s Hospital and Medical Center, New York; and the Medical Care Service Line (Drs. Arsura and Lala), Salem VAMC, VA.

Address correspondence and reprint requests to Dr. Josh Torgovnick, 31 Washington Square West, #3F, New York, NY 10011.

Cytomegalovirus ventriculoencephalitis (CMV-VE) is a devastating opportunistic infection seen most frequently in patients with AIDS. The authors describe eight patients with AIDS and CMV-VE, who developed the clinical features of the Wernicke–Korsakoff syndrome, including impaired memory, confabulation, nystagmus, ophthalmoplegia, and ataxia. CMV-VE is perhaps a more frequent cause of the Wernicke–Korsakoff syndrome than traditional associations.

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				B. L. Cucchiara, M. S. Forman, M. L. McGarvey, S. E. Kasner, and D. King Fatal Subacute Cytomegalovirus Encephalitis Associated With Hypogammaglobulinemia and Thymoma Mayo Clin. Proc., February 1, 2003; 78(2): 223 - 227. [Abstract] [PDF]