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Neurology 2000;55:468-479
© 2000 American Academy of Neurology


Special Article

Practice parameter: Screening and diagnosis of autism

Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society

P. A. Filipek, MD, P. J. Accardo, MD, S. Ashwal, MD, G. T. Baranek, PhD, OTR/L, E. H. Cook, Jr., MD, G. Dawson, PhD, B. Gordon, MD, PhD, J. S. Gravel, PhD, C. P. Johnson, MEd, MD, R. J. Kallen, MD, S. E. Levy, MD, N. J. Minshew, MD, S. Ozonoff, PhD, B. M. Prizant, PhD, CCC-SLP, I. Rapin, MD, S. J. Rogers, PhD, W. L. Stone, PhD, S. W. Teplin, MD, R. F. Tuchman, MD and F. R. Volkmar, MD

From the Departments of Pediatrics and Neurology (Dr. Filipek), University of California, Irvine, College of Medicine; Department of Pediatrics (Dr. Accardo), New York Medical College, Valhalla; Department of Pediatrics (Dr. Ashwal), Loma Linda University School of Medicine, California; Departments of Allied Health Sciences (Dr. Baranek) and Pediatrics (Dr. Teplin), University of North Carolina at Chapel Hill; Departments of Psychiatry (Dr. Cook) and Pediatrics (Drs. Cook and Kallen), University of Chicago, Illinois; Department of Psychology (Dr. Dawson), University of Washington, Seattle; Department of Neurology and Cognitive Science (Dr. Gordon), The Johns Hopkins Medical Institutions, Baltimore, Maryland; Departments of Otolaryngology (Dr. Gravel), Neurology and Pediatrics (Dr. Rapin), Albert Einstein College of Medicine, Yeshiva University, Bronx, New York; Department of Pediatrics (Dr. Johnson), University of Texas Health Science Center, San Antonio; Department of Pediatrics (Dr. Levy), University of Pennsylvania School of Medicine, Philadelphia; Department of Psychiatry and Neurology (Dr. Minshew), University of Pittsburgh School of Medicine, Pennsylvania; Departments of Psychology and Psychiatry (Dr. Ozonoff), University of Utah, Salt Lake City; Center for Study of Human Development (Dr. Prizant), Brown University, Providence, Rhode Island; Department of Psychiatry (Dr. Rogers), University of Colorado Health Sciences Center, Denver; Department of Pediatrics (Dr. Stone), Vanderbilt University Medical Center, Nashville, Tennessee; Department of Neurology (Dr. Tuchman), University of Miami School of Medicine, Florida; and Department of Child Psychiatry and the Child Study Center (Dr. Volkmar), Yale University School of Medicine, New Haven, Connecticut.

Address correspondence and reprint requests to QSS, American Academy of Neurology, 1080 Montreal Avenue, St. Paul, MN 55116; phone: 1-800-879-1960.

Autism is a common disorder of childhood, affecting 1 in 500 children. Yet, it often remains unrecognized and undiagnosed until or after late preschool age because appropriate tools for routine developmental screening and screening specifically for autism have not been available. Early identification of children with autism and intensive, early intervention during the toddler and preschool years improves outcome for most young children with autism. This practice parameter reviews the available empirical evidence and gives specific recommendations for the identification of children with autism. This approach requires a dual process: 1) routine developmental surveillance and screening specifically for autism to be performed on all children to first identify those at risk for any type of atypical development, and to identify those specifically at risk for autism; and 2) to diagnose and evaluate autism, to differentiate autism from other developmental disorders.




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