Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vedeler, C. A.
Right arrow Articles by Nyland, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vedeler, C. A.
Right arrow Articles by Nyland, H.
Neurology 2000;55:705-707
© 2000 American Academy of Neurology
Brief Communications

IgG Fc-receptor polymorphisms in Guillain–Barré syndrome

Christian A. Vedeler, MD, Guttorm Raknes, MS, Kjell–Morten Myhr, MD and Harald Nyland, MD

From the Department of Neurology, Haukeland Hospital, University of Bergen, Norway.

Address correspondence and reprint requests to Dr. Christian A. Vedeler, Department of Neurology, Haukeland Hospital, N-5021 Bergen, Norway; e-mail: Christian.A.Vedeler{at}nevro.haukeland.no

The authors studied immunoglobulin G (IgG) Fc receptor (Fc{gamma}R) IIA, IIIA, and IIIB polymorphisms in 62 patients with Guillain–Barré syndrome (GBS) and in 89 healthy controls. The Fc{gamma}R genotypes and allele frequencies did not differ significantly between the patients with GBS and the controls. Patients homozygous for the Fc{gamma}RIIIB neutrophil antigen (NA) 1 allele had a significantly less severe disease than patients heterozygous or homozygous for the NA2 allele. The Fc{gamma}RIIIB NA1/NA1 genotype has high affinity for IgG1 and IgG3, and clearance of circulating autoantibodies and immune complexes may therefore be of importance in the pathogenesis of GBS.




This article has been cited by other articles:


Home page
 GlycobiologyHome page
K. Kaida, T. Ariga, and R. K Yu
Antiganglioside antibodies and their pathophysiological effects on Guillain-Barre syndrome and related disorders--A review
Glycobiology, July 1, 2009; 19(7): 676 - 692.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
A. Musolino, N. Naldi, B. Bortesi, D. Pezzuolo, M. Capelletti, G. Missale, D. Laccabue, A. Zerbini, R. Camisa, G. Bisagni, et al.
In Reply
J. Clin. Oncol., November 20, 2008; 26(33): 5491 - 5492.
[Full Text] [PDF]

Home page
 Clin. Microbiol. Rev.Home page
R. Janssen, K. A. Krogfelt, S. A. Cawthraw, W. van Pelt, J. A. Wagenaar, and R. J. Owen
Host-Pathogen Interactions in Campylobacter Infections: the Host Perspective
Clin. Microbiol. Rev., July 1, 2008; 21(3): 505 - 518.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
N.-K. V. Cheung, R. Sowers, A. J. Vickers, I. Y. Cheung, B. H. Kushner, and R. Gorlick
FCGR2A Polymorphism Is Correlated With Clinical Outcome After Immunotherapy of Neuroblastoma With Anti-GD2 Antibody and Granulocyte Macrophage Colony-Stimulating Factor
J. Clin. Oncol., June 20, 2006; 24(18): 2885 - 2890.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
M. S. G. Kwa, I. N. van Schaik, R. R. De Jonge, A. Brand, L. Kalaydjieva, N. van Belzen, M. Vermeulen, and F. Baas
Autoimmunoreactivity to Schwann cells in patients with inflammatory neuropathies
Brain, February 1, 2003; 126(2): 361 - 375.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2000 by AAN Enterprises, Inc.