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Neurology 2000;55:1045-1048
© 2000 American Academy of Neurology


Brief Communications

Complications during apnea testing in the determination of brain death: Predisposing factors

John L. Goudreau, DO, PhD, Eelco F. M. Wijdicks, MD and Steve F. Emery, BA

From the Neurological–Neurosurgical Intensive Care Unit, Department of Neurology (Drs. Goudreau and Wijdicks), Saint Mary’s Hospital, Mayo Medical Center; and LifeSource (Upper Midwest Organ Procurement Organization, Inc.) (S.F. Emery), Rochester, MN.

Address correspondence and reprint requests to Dr. E.F.M. Wijdicks, Mayo Clinic, W8B, 200 First Street SW, Rochester, MN 55905; e-mail: wijde{at}mayo.edu

Apnea testing in brain death determination may result in cardiovascular complications. Hypotension occurred in 24% and cardiac arrhythmias occurred in <1% of the 145 apneic oxygenation procedures. Complications were noted in only 15% of apnea tests performed without any predisposing factors. Significantly more complications (39%) were observed in apnea tests with inadequate precautions, particularly in apnea tests without adequate preoxygenation (50%).




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