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Neurology 2000;55:1393-1396
© 2000 American Academy of Neurology
Brief Communications

Discontinuation of anticonvulsant therapy in children with partial epilepsy

A. Verrotti, MD, PhD, S. Morresi, MD, F. Basciani, RD, R. Cutarella, MD, G. Morgese, MD and F. Chiarelli, MD

From the Department of Medicine (Dr. Verrotti), Section of Pediatrics, University of Chieti; Department of Neurology (Dr. Cutarella), S. Valentino Hospital; and Department of Pediatrics (Dr. Morgese), University of Siena, Italy.

Address correspondence and reprint requests to Dr. Alberto Verrotti, Department of Medicine, Section of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66013 Chieti, Italy; e-mail: averrott{at}obelix.unich.it

To evaluate when it is possible to discontinue anticonvulsant treatment in children with cryptogenic partial epilepsy, the authors studied 89 epileptic children divided into two groups: Group A, 45 children whose therapy was discontinued after 1 year from the last seizure; and Group B, 44 children whose therapy was stopped after 2 years from the last seizure. After 5 years of follow-up, the recurrence rate was similar in the two groups of patients (Group A, 28.8%; Group B, 25%). It is safe to discontinue the anticonvulsant therapy in children with cryptogenic partial epilepsy who were seizure free for only 1 year.




This article has been cited by other articles:


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J. G. Serra, M. A. Montenegro, and M. M. Guerreiro
Antiepileptic Drug Withdrawal in Childhood: Does the Duration of Tapering Off Matter for Seizure Recurrence?
J Child Neurol, July 1, 2005; 20(7): 624 - 626.
[Abstract] [PDF]


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