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From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
Address correspondence and reprint requests to Dr. SM Wong, Department of Medicine, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong, China; e-mail: jsmwong{at}hkstar.com
The authors compared the effectiveness of low-dose, short-term oral prednisolone vs local methylprednisolone injection in a prospective, double-blinded, parallel treatment study of carpal tunnel syndrome (CTS). A single injection of 15 mg methylprednisolone resulted in significant improvement in global symptom scores over a 12-week period. This study demonstrated the superiority of local steroid injection to oral steroid in the treatment of CTS.
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