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Rescue treatment with abciximab in acute ischemic stroke

From the Departments of Neurology (Drs. K.Y. Lee and Heo) and Neuroradiology (Drs. S.I. Lee and Yoon), Yonsei University College of Medicine, Seoul, Korea.

Address correspondence and reprint requests to Dr. Ji Hoe Heo, Department of Neurology, Yonsei University College of Medicine, C.P.O. Box 8044, 120-752 Seoul, Korea; e-mail: jhheo@yumc.yonsei.ac.kr

In acute ischemic stroke, reocclusion after an initially successful thrombolysis treatment can occur and is associated with increased morbidity and mortality. The authors present the successful use of abciximab, a platelet glycoprotein IIb/IIIa receptor inhibitor, in a patient with a thrombotic occlusion of the proximal middle cerebral artery, which was refractory to combined IV and intra-arterial thrombolysis and percutaneous intracranial balloon angioplasty.

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