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Neurology 2001;56:251-253
© 2001 American Academy of Neurology
Brief Communications

Postictal stability of proton magnetic resonance spectroscopy imaging (1H-MRSI) ratios in temporal lobe epilepsy

B. Maton, MD, A. Londoño, MD, S. Sawrie, PhD, R. Knowlton, MD, R. Martin, PhD and R. Kuzniecky, MD

From the UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham.

Address correspondence and reprint requests to Dr. R. Kuzniecky, UAB Epilepsy Center, 1719 6th Avenue South, CIRC 312, Birmingham, AL 35294-0021.

Interictal proton (1H) MRS is increasingly used for seizure lateralization in patients with temporal lobe epilepsy (TLE). Studies reporting postictal 1H-MRS metabolite changes in patients with TLE are few and contradictory. The authors prospectively performed interictal and postictal proton magnetic resonance spectroscopy imaging (1H-MRSI) studies in seven patients with TLE. The authors found no consistent changes in metabolite peak area ratios between studies, suggesting that 1H-MRS ratios remain stable between interictal and postictal state in TLE.




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K. Kantarci, C. Shin, J. W. Britton, E. L. So, G. D. Cascino, and C. R. Jack Jr.
Comparative diagnostic utility of 1H MRS and DWI in evaluation of temporal lobe epilepsy
Neurology, June 25, 2002; 58(12): 1745 - 1753.
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