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Neurology 2001;56:273-275
© 2001 American Academy of Neurology
Brief Communications

Post-traumatic chronic paroxysmal hemicrania (CPH) with aura

Manjit S. Matharu, MRCP; and Peter J. Goadsby, MD, DSc

From the Headache Group, Institute of Neurology, and the National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Address correspondence and reprint requests to Professor Peter J. Goadsby, Institute of Neurology, Queen Square, London WC1N 3BG, UK; e-mail: peterg{at}brain.ion.ucl.ac.uk

The authors describe a patient who developed chronic paroxysmal hemicrania (CPH) in close temporal relationship to a head injury. The subsequent attacks of CPH were associated with a typical migrainous sensory and motor aura. Administration of indomethacin 75 mg daily resulted in isolated occurrence of autonomic and aura symptoms in the absence of pain symptoms. The patient became completely asymptomatic on indomethacin 100 mg daily. Migrainous aura may be seen with trigeminal-autonomic headaches and may represent the expression of an aura-susceptibility gene rather than typical migraine headache biology.




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