HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Supplemental figures Appendix Correspondence: Submit a response Correspondence: View responses Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Staines, W.R. Articles by Black, S.E. Search for Related Content PubMed PubMed Citation Articles by Staines, W.R. Articles by Black, S.E.

Bilateral movement enhances ipsilesional cortical activity in acute stroke: A pilot functional MRI study

From the Sunnybrook and Women’s College Health Sciences Centre (Drs. Staines, McIlroy, Graham, and Black), Departments of Medicine (Neurology) (Drs. Staines, McIlroy, and Black) and Medical Biophysics (Dr. Graham), and Graduate Department of Rehabilitation Science (Drs. Staines and McIlroy), University of Toronto, Ontario, Canada.

Address correspondence and reprint requests to Dr. W.R. Staines, Cognitive Neurology, A421, Sunnybrook and Women’s College Health Science Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5; e-mail: r.staines{at}utoronto.ca

Functional MRI was performed in two acute stroke patients and six control subjects performing unilateral and bilateral repetitive gripping tasks. Patients were tested at three time points during recovery. Initially, bilateral movement enhanced activation in the primary motor cortex (M1) of the affected hemisphere compared with unilateral paretic hand movement. With recovery, activation of M1 in the affected hemisphere did not differ between unilateral paretic hand and bilateral movement. These preliminary data may have potential implications for acute stroke motor rehabilitation.

This article has been cited by other articles:

				B. J. MacIntosh, W. E. McIlroy, R. Mraz, W. R. Staines, S. E. Black, and S. J. Graham Electrodermal Recording and fMRI to Inform Sensorimotor Recovery in Stroke Patients Neurorehabil Neural Repair, November 1, 2008; 22(6): 728 - 736. [Abstract] [PDF]

				N. Shinoura, Y. Suzuki, R. Yamada, T. Kodama, M. Takahashi, and K. Yagi Restored Activation of Primary Motor Area from Motor Reorganization and Improved Motor Function after Brain Tumor Resection AJNR Am. J. Neuroradiol., June 1, 2006; 27(6): 1275 - 1282. [Abstract] [Full Text] [PDF]

				S. Hesse, C. Werner, M. Pohl, S. Rueckriem, J. Mehrholz, and M.L. Lingnau Computerized Arm Training Improves the Motor Control of the Severely Affected Arm After Stroke: A Single-Blinded Randomized Trial in Two Centers Stroke, September 1, 2005; 36(9): 1960 - 1966. [Abstract] [Full Text] [PDF]

				F. Binkofski and R. J. Seitz Modulation of the BOLD-response in early recovery from sensorimotor stroke Neurology, October 12, 2004; 63(7): 1223 - 1229. [Abstract] [Full Text] [PDF]

				D. J. Gladstone, S. E. Black, and A. M. Hakim Toward Wisdom From Failure: Lessons From Neuroprotective Stroke Trials and New Therapeutic Directions Stroke, August 1, 2002; 33(8): 2123 - 2136. [Abstract] [Full Text] [PDF]

				M. Hallett Recent Advances in Stroke Rehabilitation Neurorehabil Neural Repair, June 1, 2002; 16(2): 211 - 217. [PDF]

				M. L. Cuadrado, J. A. Arias, W. R. Staines, W. E. McIlroy, S. J. Graham, and S. E. Black Bilateral movement enhances ipsilesional cortical activity in acute stroke: A pilot functional MRI study Neurology, November 13, 2001; 57(9): 1740 - 1741. [Full Text] [PDF]

				M. H. Mudie and T. A. Matyas Responses of the Densely Hemiplegic Upper Extremity to Bilateral Training Neurorehabil Neural Repair, March 1, 2001; 15(2): 129 - 140. [Abstract] [PDF]

Correspondence: