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Changes in referral pattern and its effect on outcome in patients with Guillain–Barré syndrome

From the Departments of Neurology (Drs. Van Koningsveld, Van Doorn, and Van der Meché) and Statistics (Dr.Schmitz), Erasmus University Medical Centre Rotterdam, the Netherlands.

Address correspondence and reprint requests to Dr. R. Van Koningsveld, Department of Neurology, Erasmus Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, the Netherlands; e-mail: vankoningsveld{at}neuro.fgg.eur.nl

The authors assessed the referral pattern and outcome in patients with Guillain–Barré syndrome (n = 266) after the introduction of intravenous immunoglobulin (IVIg). Fewer patients were transferred from small to large hospitals after the introduction of IVIg (p = 0.05). This did not result in a worse outcome in patients treated in small centers. The introduction of IVIg has led to a better use of different levels of health care facilities.