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Relative pupil-sparing third nerve palsy: Etiology and clinical variables predictive of a mass

From the Departments of Neurology and Ophthalmology, Marshfield Clinic, WI.

Address correspondence and reprint requests to Dr. Daniel M. Jacobson, Neuro-ophthalmology (4F-2), Marshfield Clinic, 1000 N. Oak Avenue, Marshfield, WI 54449; e-mail: jacobsod{at}mfldclin.edu

The causes of ophthalmoplegia in 24 consecutive patients with neurologically isolated, relative pupil-sparing third nerve palsy included infarction in 10 patients, compression by tumors or aneurysms in 10 patients, and miscellaneous disorders in four patients. There was no significant difference in the proportion of patients with pain, degree of external ophthalmoplegia, or degree of internal ophthalmoplegia between the groups with infarction or mass lesions. Therefore, screening for mass lesions using neuroimaging is indicated in patients with this presentation of third nerve palsy.

This article has been cited by other articles:

				K. Ikeda, M. Tamura, Y. Iwasaki, M. Kinoshita, and D. M. Jacobson Relative pupil-sparing third nerve palsy: Etiology and clinical variables predictive of a mass Neurology, November 13, 2001; 57(9): 1741 - 1742. [Full Text] [PDF]

				Is Pupil Size a Useful Diagnostic Finding in Third Nerve Palsy? Journal Watch Neurology, June 28, 2001; 2001(628): 5 - 5. [Full Text]

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