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Neurology 2001;56:799-802
© 2001 American Academy of Neurology
Brief Communications

Outcomes following staged bilateral pallidotomy in advanced Parkinson’s disease

T.J. Counihan, MD, MRCPI;, L.A. Shinobu, MD, PhD;, E.N. Eskandar, MD;, G.R. Cosgrove, MD, FRCS(C); and J.B. Penney Jr., MD*

From the Departments of Neurology (Drs. Counihan, Shinobu, and Penney) and Neurosurgery (Drs. Eskandar and Cosgrove), Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Address correspondence and reprint requests to Dr. Timothy J. Counihan, Department of Neurology, Box 673, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642; e-mail: timothycounihan{at}urmc.rochester.edu

The authors assessed clinical outcome for up to one year after staged bilateral pallidotomy in 14 patients with advanced PD. One year after surgery, dyskinesias were virtually abolished and there were significant reductions in "off" time (67%) and activities of daily living "off" scores (24%), as well as nonsignificant reduction in "off" motor score (39%); "on" scores were unchanged. One patient developed a visual field deficit; two had transient confusion. Staged bilateral pallidotomy improves motor function in selected patients with advanced PD.




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