HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Fernandez, H. H. Articles by Friedman, J. H. Search for Related Content PubMed PubMed Citation Articles by Fernandez, H. H. Articles by Friedman, J. H.

The course of tardive dyskinesia and parkinsonism in psychiatric inpatients: 14-year follow-up

From the Division of Neurology (Drs. Fernandez and Friedman), Memorial Hospital of Rhode Island, Pawtucket; the Department of Psychiatry (Dr. Krupp), Eleanor Slate Hospital, Cranston; and the Departments of Neurology and Psychiatry (Drs. Fernandez and Friedman), Brown University School of Medicine, Providence, RI.

Address correspondence and reprint requests to Dr. Hubert H. Fernandez, Division of Neurology, Memorial Hospital of Rhode Island, 111 Brewster Street, Pawtucket, RI 02860; e-mail: fernandezh{at}pol.net

Tardive dyskinesia and parkinsonism were assessed in 53 patients residing in a state psychiatric hospital in 1984 and 1998. A 4.0-point decrease in the mean Abnormal Involuntary Movement Scale score (6.0 versus 2.0; p < 0.001) and a 3.5-point increase in the Rating Scale for Extrapyramidal Signs score (2.8 versus 6.3; p < 0.001) were noted between 1984 and 1998. Over a 14-year period, tardive dyskinesia improved and parkinsonism worsened in patients who continued to receive neuroleptic drugs.