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Neurology 2001;56:810-813
© 2001 American Academy of Neurology
Brief Communications

Neurologic manifestations of disseminated infection with Mycobacterium abscessus

David S. Liebeskind, MD;, Nora Ostrzega, MD;, Claude G. Wasterlain, MD; and Edgar A. Buttner, MD, PhD

From the Comprehensive Stroke Center (Dr. Liebeskind), University of Pennsylvania, Philadelphia, PA; the Departments of Pathology (Dr. Ostrzega), and Neurology (Dr. Wasterlain), UCLA School of Medicine, Los Angeles, CA; the Department of Biology (Dr. Buttner), Howard Hughes Medical Institute, MIT, Cambridge, MA; and the Department of Neurology (Dr. Buttner), Massachusetts General Hospital, Boston, MA.

Address correspondence and reprint requests to Dr. David S. Liebeskind, Comprehensive Stroke Center, University of Pennsylvania Medical Center, 3 West Gates Building, 3400 Spruce Street, Philadelphia, PA 19104-4283; e-mail: davidliebeskind{at}yahoo.com

Mycobacterium abscessus is a ubiquitous, saprophytic organism with low pathogenic potential. The authors describe the previously unreported clinical features of meningitis and native valve endocarditis caused by this rapidly growing atypical mycobacterium. The fatal outcome of this unusual case coincides with the grim prognosis of this disseminated infection and the significant mortality rate associated with neurologic complications of infective endocarditis.






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